I-O Optimise rationale and methodology publications

S Ekman, F Griesinger, P Baas, D Chao, C Chouaid, JC O'Donnell, JR Penrod, M Daumont, L Lacoin, A McKenney, M Khovratovich, RE Munro, I Durand-Zaleski, SP Johnsen.
I-O Optimise: a novel multinational real-world research platform in thoracic malignancies. Future Oncol. 2019;15:1551–1563.

https://www.futuremedicine.com/doi
/10.2217/fon-2019-0025

I-O Optimise data publications

M Soares, L Antunes, P Redondo, M Borges, R Hermans, D Patel, F Grimson, R Munro, C Chaib, L Lacoin, M Daumont, JR Penrod, JC O'Donnell, MJ Bento, FR Gonçalves.
Real-world treatment patterns and survival outcomes for advanced non-small cell lung cancer in the pre-immunotherapy era in Portugal: a retrospective analysis from the I-O Optimise initiative. BMC Pulm Med. 2020;20:240.

https://bmcpulmmed.biomedcentral.com/
track/pdf/10.1186/s12890-020-01270-z.pdf

M Soares, L Antunes, P Redondo, M Borges, R Hermans, D Patel, F Grimson, R Munro, C Chaib, L Lacoin, M Daumont, JR Penrod, JC O'Donnell, MJ Bento, FR Gonçalves.
Treatment and outcomes for early non-small-cell lung cancer: a retrospective analysis of a Portuguese hospital database. Lung Cancer Manag. 2021;10:LMT46.

https://www.ncbi.nlm.nih.gov/pmc/
articles/PMC8162184/pdf/lmt-10-46.pdf

S Ekman, P Horvat, M Rosenlund, AM Kejs, D Patel, A Juarez-Garcia, L Lacoin, MJ Daumont, JR Penrod, OT Brustugun, JB Sørensen.
Epidemiology and survival outcomes for patients with NSCLC in Scandinavia in the preimmunotherapy era: a SCAN-LEAF retrospective analysis from the I-O Optimise initiative. JTO Clin Res Rep. 2021;2:100165.

https://www.jtocrr.org/article/S2666-3643(21)00024-2/pdf

M Snee, S Cheeseman, M Thompson, M Riaz, W Sopwith, L Lacoin, C Chaib, MJ Daumont, JR Penrod, JC O'Donnell, G Hall.
Trends in the prescription of systemic anticancer therapy and mortality among patients with advanced non-small cell lung cancer: a real-world retrospective observational cohort study from the I-O Optimise initiative. BMJ Open. 2021;11:e043442.

https://bmjopen.bmj.com/content/
bmjopen/11/5/e043442.full.pdf

M Snee, S Cheeseman, M Thompson, M Riaz, W Sopwith, L Lacoin, C Chaib, MJ Daumont, JR Penrod, G Hall.
Treatment patterns and survival outcomes for patients with non-small cell lung cancer in the UK in the preimmunology era: a REAL-Oncology database analysis from the I-O Optimise initiative. BMJ Open. 2021;11:e046396.

https://bmjopen.bmj.com/content/
11/9/e046396.long

P Baas, MJ Daumont, L Lacoin, JR Penrod, R Carroll, S Venkatesh, A Ubhi, M Snee.
Treatment patterns and outcomes for patients with malignant pleural mesothelioma in England in 2013-2017: a nationwide CAS registry analysis from the I-O Optimise initiative. Lung Cancer. 2021;162:185–193.

https://www.annalsofoncology.org/article/
S0923-7534(20)41448-6/fulltext

JB Sorensen, P Horvat, M Rosenlund, AM Kejs, D Patel, A Juarez-Garcia, L Lacoin, MJ Daumont, JR Penrod, JC O'Donnell, OT Brustugun, S Ekman.
Initial treatment and survival in Danish patients diagnosed with non-small-cell lung cancer (2005-2015): SCAN-LEAF study. Future Oncol. 2022;18:205–214.

https://www.futuremedicine.com/doi/full/
10.2217/fon-2021-0746?rfr_dat=
cr_pub++0pubmed&url_ver=Z39.88-200
3&rfr_id=ori%3Arid%3Acrossref.org

R Carroll, M Bortolini, A Calleja, R Munro, S Kong, MJ Daumont, JR Penrod, K Lakhdari, L Lacoin, WY Cheung.
Trends in treatment patterns and survival outcomes in advanced non-small cell lung cancer: a Canadian population-based real-world analysis. BMC Cancer. 2022 Mar 10;22(1):255.

https://bmccancer.biomedcentral.com/
articles/10.1186/s12885-022-09342-5

F Griesinger, M Pérol, N Girard, I Durand-Zaleski, S Zacharias, L Bosquet, M Jänicke, X Quantin, A Groth, A Fleitz, A Calleja, S Patel, L Lacoin, MJ Daumont, JR Penrod, R Carroll, D Waldenberger, D Reynaud, M Thomas, C Chouaid.
Impact of immune checkpoint inhibitors on the management of locally advanced or metastatic non-small cell lung cancer in real-life practice in patients initiating treatment between 2015 and 2018 in France and Germany. Lung Cancer. 2022 Oct;172:65-74.

https://www.lungcancerjournal.info/article/
S0169-5002(22)00577-3/fulltext

C Chouaid, M Thomas, D Debieuvre, I Durand-Zaleski, S Zacharias, L Bosquet, A Groth, A Fleitz, A Calleja, S Patel, L Lacoin, MJ Daumont, JR Penrod, R Carroll, D Waldenberger, F-E Cotté, C Audigier-Valette, F Griesinger.
Effectiveness of nivolumab in second-Line and later in patients with advanced non-small cell lung cancer in real-life practice in France and Germany: analysis of the ESME-AMLC and CRISP cohorts. Cancers. 2022;14(24): 6148.

https://www.mdpi.com/2072-6694/14/24/6148

A Wolf, JA Stratmann, S Shaid, N Niklas, A Calleja, H Ubhi, R Munro, D Waldenberger, R Carroll, MJ Daumont, JR Penrod, L Lacoin, G Rohde.
Evolution of treatment patterns and survival outcomes in patients with advanced non-small cell lung cancer treated at Frankfurt University Hospital in 2012-2018. BMC Pulm Med. 2023 Jan 13;23(1):16.

https://bmcpulmmed.biomedcentral.com/
articles/10.1186/s12890-022-02288-1