Advice is provided by a multidisciplinary team of experts (clinicians, epidemiologists, health economists, and data source owners) who make up the independent ESC, which provides:
- Tactical/evaluative input – evaluate scientific protocols, analyses, and outputs
- Strategic guidance – advise on research prioritization and publication focus
- Advice on external engagement – support external communications (ie, publications, congress presentations, and other outreach activities)
In addition to the ESC, a larger group of consultants, including clinicians, epidemiologists, nurses, data source owners, and patient advocates, is convened regularly as part of the I-O Optimise Consortium program. The various Consortium workstreams are designed to (i) provide additional input on the program’s research objectives and related methodologies, (ii) foster collaboration between partner data sources and stakeholders, and (iii) raise the profile of I-O Optimise through advising on the optimal external dissemination of research outputs.